Antimicrobial Resistance Patterns of Enteric Bacteria Isolated from Diarrhoeic Patients Attending Selected Hospitals in Akure, Nigeria
,
Click an author's name to view their details
Abstract
Diarrhoea remains a major public health challenge worldwide, particularly in developing countries where poor sanitation, unsafe water and inadequate hygiene contribute significantly to disease transmission. The increasing emergence of antimicrobial-resistant enteric bacteria, especially extended-spectrum β-Lactamase (ESBL) producing organisms, has complicated the treatment and management of diarrhoeal infections. This study aimed to evaluate the occurrence of ESBL-production among antibiotic-resistant bacterial isolates obtained from diarrhoeic patients. A total of 367 stool samples were collected from patients attending selected hospitals in Akure, Ondo State, Nigeria, comprising 17 diarrhoeic and 350 non-diarrhoeic samples. Standard microbiological techniques were employed for the isolation and identification of bacterial pathogens, while antibiotic susceptibility testing was performed using standard antimicrobial sensitivity methods. ESBL production was phenotypically detected using appropriate confirmatory methods on multidrug-resistant bacterial isolates. The study identified several enteric bacterial pathogens associated with diarrhoeal infections, including Escherichia coli, Proteus mirabili and the species of Salmonella, Shigella, Klebsiella and Enterobacter. Antibiotic susceptibility testing revealed varying degrees of resistance to commonly used antibiotics, with several isolates demonstrating multidrug resistance. 6.7% of isolates were resistant to ofloxacin, 37.8 % to augmentine, 18.9% to peflacine, 45.9% to ceftazidime, 13.5% to gentamycin, 59.46% to ciprofloxacin, 17.5% to ceporex, 40.5% to ceftriaxone, 9.4% to streptomycin and 32.4% to cefuroxime. ESBL-producing isolates were detected among the bacterial pathogens, suggesting the circulation of resistant enteric bacteria within the study population. The findings of this study highlight the growing threat of ESBL-producing enteric bacteria in diarrhoea diseases and emphasize the need for continuous surveillance, effective infection prevention measures and rational antibiotic use to reduce the spread of antimicrobial resistance.
📄 Read Full Text Open in new tab ↗
How to Cite
Adeleke, R. A., & Onifade, A. K. (2026). Antimicrobial Resistance Patterns of Enteric Bacteria Isolated from Diarrhoeic Patients Attending Selected Hospitals in Akure, Nigeria. Journal of Contemporary Academic Research and Methodologies, 1(8), Article 047. https://doi.org/10.5281/zenodo.23433050
Adeleke, Rofiat Abidemi, and Anthony Kayode Onifade. "Antimicrobial Resistance Patterns of Enteric Bacteria Isolated from Diarrhoeic Patients Attending Selected Hospitals in Akure, Nigeria." Journal of Contemporary Academic Research and Methodologies, vol. 1, no. 8, 2026, article 047. DOI: https://doi.org/10.5281/zenodo.23433050
Adeleke, Rofiat Abidemi, and Anthony Kayode Onifade. "Antimicrobial Resistance Patterns of Enteric Bacteria Isolated from Diarrhoeic Patients Attending Selected Hospitals in Akure, Nigeria." Journal of Contemporary Academic Research and Methodologies 1, no. 8 (2026): 047. https://doi.org/10.5281/zenodo.23433050
References
This article is published under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. Free to read, share, and adapt with attribution.